Gleason score

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Glea·son tu·mor grade

a classification of adenocarcinoma of the prostate by evaluation of the pattern of glandular differentiation; the tumor grade, known as Gleason score, is the sum of the dominant and secondary patterns, each numbered on a scale of 1 to 5.

Gleason score

Oncology A value derived from the Gleason grading system which is the sum of the 2 most predominant histologic patterns seen in prostate CA.

Gleason score

A method of grading malignancy of prostate cancers, based on the pattern of glandular differentiation. Both the dominant and secondary patterns of differentiation are scored on a scale of 1 to 5, and the Gleason score, is the sum of the two scores.


Donald F., U.S. pathologist, 1920–.
Gleason score
Gleason tumor grade - a classification of adenocarcinoma of the prostate.
References in periodicals archive ?
He said: "The prostate and various other bits that were taken out were examined and it turned out I had a Gleason Score of nine [of a maximum of 10].
He said: "They took the prostate out, they took 11 lymph nodes out, the various bits that were taken out were examined and it turned out I had a Gleason Score of nine after considering 10 is the maximum, it was clearly an aggressive little bugger.
High adherers to a Mediterranean-style diet had a significant mean 33% lower risk for PCa above Gleason score 6 and a 51% lower risk for clinical stage T2b to T4 disease.
Histologic grade is a valuable factor used in assessing prognosis and selecting treatment for patients with many forms of cancer, and this is especially true regarding the Gleason score for men with prostate cancer.
To be on the safe side Dan's doctor did a Gleason score which distinguishes between benign prostate disease and cancer.
It is wise to assess adjunctive SM features such as SM, length, Gleason score and grade, and decide according to the patients' risk groups to decide on adjuvant treatment.
9] The Gleason score and prostate-specific antigen (PSA) level are the most important prognostic factors in prostate cancer.
Col IV and Fn distribution in prostatic adenocarcinoma and correlation of 67LR, MMP-9 and TIMP-1 expression with Gleason score.
To gauge your eligibility for surveillance, your doctor will consider your age, life expectancy, the amount of cancer retrieved during your prostate biopsy, Gleason score, and prostate-specific antigen (PSA) level, and will also determine your cancer's risk level.
Histopathological analysis showed adenocarcinoma with a Gleason score of 5 (3 + 2).
Patients with organ confined disease were further sub-stratified according to the D'Amico classification (11) into low (PSA < 10 ng/ ml, Gleason score 6, clinical stage T1-T2a), intermediate (PSA 10-20 ng/ml, Gleason score 7, clinical stage T2b) and high risk disease (PSA > 20 ng/ml, Gleason score [greater than or equal to] 8, clinical stage T2c-T3a), indicating risk of failure after curative treatment.