Gleason score

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Glea·son tu·mor grade

a classification of adenocarcinoma of the prostate by evaluation of the pattern of glandular differentiation; the tumor grade, known as Gleason score, is the sum of the dominant and secondary patterns, each numbered on a scale of 1 to 5.

Gleason score

Oncology A value derived from the Gleason grading system which is the sum of the 2 most predominant histologic patterns seen in prostate CA.

Gleason score

A method of grading malignancy of prostate cancers, based on the pattern of glandular differentiation. Both the dominant and secondary patterns of differentiation are scored on a scale of 1 to 5, and the Gleason score, is the sum of the two scores.


Donald F., U.S. pathologist, 1920–.
Gleason score
Gleason tumor grade - a classification of adenocarcinoma of the prostate.
References in periodicals archive ?
Decipher offers valuable insight that is distinct from clinical measures of risk including PSA and Gleason score.
Robert's PSA was not off the charts, but his Gleason score was also high.
The authors have also provided helpful information about patient-and cancer-related parameters associated with upgrading to Gleason score 7 or greater at surveillance biopsy.
The percentage of ductal cancer, the highest Gleason score, and the location of the ductal cancer were recorded.
In a new analysis, researchers compared 489 men in the study who were diagnosed with high-grade prostate cancer (a Gleason score of 7 to 10) during the trial to 3,117 men in the study without prostate cancer.
The Gleason score is one measure of a patient's specific risk of dying due to prostate cancer.
Among cancer cases the rate of ordering was highest for Gleason score 3 + 3 = 6 relative to all other grades of cancers.
A microfocal cancer (MFC) was defined by a single core involved with [less than or equal to] 3 mm of Gleason score 3 + 3 cancer.
Material and methods: In this study, specimens from 71 patients with clinically localized prostate cancer who underwent RP between January 2007 and January 2011 in our department, who regularly attended their follow-up visits and who had a Gleason score of 5-8 (5 and 8 included) were reanalyzed by a single pathologist.
We present measurements in plasma of prostate cancer patients characterised by PSA, tumour stage and Gleason score using GC/MS for sarcosine methodology (9,10) to elaborate further on the suitability of sarcosine as a marker for prostate cancer.
So an expert came up with a scoring system to rank the malignancy of a prostate tumour - the Gleason Score.