KLK2

(redirected from Glandular kallikrein-1)

KLK2

A gene on chromosome 19q13.33 that encodes a serine protease with diverse physiological functions, which may also have a role in carcinogenesis. KLK2 is highly expressed in prostate cancer and may serve as a prognostic marker for prostate cancer.
References in periodicals archive ?
Identification and androgen-regulated expression of two major human glandular kallikrein-1 (hGK-1) mRNA species.
(b) Full gene names are as follows: hPRK, human pancreatic/renal kallikrein; hGK-1, human glandular kallikrein-1; KLK-L, kallikrein-like; EMSP1, enamel matrix serine proteinase 1; HSCTE, human stratum corneum tryptic enzyme; HSCCE, human stratum corneum chymotryptic enzyme; TADG-14, tumor-associated, differentially expressed gene-14; NES1, normal epithelial cell-specific 1 gene; TLSP, trypsin-like serine protease; PRSS, protease serine; PRSSL, protease serine-like.
The prostate specific antigen gene and the human glandular kallikrein-1 gene are tandemly located on chromosome 19.