Giant Mitochondria

Massively enlarged mitochondria that appear as pale rounded eosinophilic masses by light microscopy, which mimic both red cells and Mallory’s hyaline; the finding of giant mitochondria in hepatocytes is nonspecific but characteristic of all phases of alcoholic liver disease, ranging from fatty liver to cirrhosis
References in periodicals archive ?
Lim et al., "Formation of elongated giant mitochondria in DFO-induced cellular senescence: involvement of enhanced fusion process through modulation of Fis1," Journal of Cellular Physiology, vol.
Myelin-like structures and some vacuoles in cytoplasm, giant mitochondria formation, and enlargement of intercellular space in intercalated disk were observed.
(b) Fusion of mitochondria, formation of giant mitochondria, and myelin-like structures within cardiomyocyte cytoplasm (arrow).