gestational trophoblastic disease

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hy·da·tid·i·form mole

, hydatid mole [MIM*231090]
a vesicular or polycystic mass resulting from the proliferation of the trophoblast, with hydropic degeneration and avascularity of the chorionic villi; the abnormal tissue typically results from expression of paternally derived chromosomes and a loss of maternal chromosomes.

gestational trophoblastic disease

A generic term for a group of pregnancy-related disorders that arise from the trophoblast and clinically range from banal (e.g., hydatidiform mole) to aggressively malignant (e.g., choriocarcinoma).

Gestational trophoblastic disease
Hydatidiform mole
• Complete mole
• Partial mole
• Invasive mole
Placental site trophoblastic tumour
Epithelioid trophoblastic tumour

gestational trophoblastic disease

Gynecology A general term for the proliferative processes arising in trophoblastic tissue in ♀ of child-bearing age Types Gestational trophoblastic tumor/neoplasia, molar pregnancy, choriocarcinoma. See Choriocarcinoma, Mole, Trophoblastic tumor.

Gestational trophoblastic disease

A rare, aggressive, malignant, often metastatic (spreading to other organs) cancer in women of childbearing age in which cancer cells grow in the tissues that are formed in the uterus after conception
References in periodicals archive ?
Recent advances in gestational trophoblastic disease.
hCG is synthesized and secreted by trophoblastic tissue of the placenta in pregnancy, gestational trophoblastic diseases, and certain other pathological conditions (2-5).
Tumors of the Uterine Corpus and Gestational Trophoblastic Disease.
Additional serum samples were collected from 12 women erroneously diagnosed as having choriocarcinoma or gestational trophoblastic disease because of false-positive hCG results (16,17).
Hydatidiform mole is a gestational trophoblastic disease and includes complete and partial moles.
That the presence of hCG[beta] mRNA in the peripheral blood reflects circulating tumor cells has previously been shown in metastatic breast cancer (14), germ-cell tumors (15), and gestational trophoblastic disease (16).