gestational trophoblastic disease


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hy·da·tid·i·form mole

, hydatid mole [MIM*231090]
a vesicular or polycystic mass resulting from the proliferation of the trophoblast, with hydropic degeneration and avascularity of the chorionic villi; the abnormal tissue typically results from expression of paternally derived chromosomes and a loss of maternal chromosomes.

gestational trophoblastic disease

A generic term for a group of pregnancy-related disorders that arise from the trophoblast and clinically range from banal (e.g., hydatidiform mole) to aggressively malignant (e.g., choriocarcinoma).

Gestational trophoblastic disease
Hydatidiform mole
• Complete mole
• Partial mole
• Invasive mole
Placental site trophoblastic tumour
Epithelioid trophoblastic tumour
Choriocarcinoma

gestational trophoblastic disease

Gynecology A general term for the proliferative processes arising in trophoblastic tissue in ♀ of child-bearing age Types Gestational trophoblastic tumor/neoplasia, molar pregnancy, choriocarcinoma. See Choriocarcinoma, Mole, Trophoblastic tumor.

Gestational trophoblastic disease

A rare, aggressive, malignant, often metastatic (spreading to other organs) cancer in women of childbearing age in which cancer cells grow in the tissues that are formed in the uterus after conception
References in periodicals archive ?
Gestational trophoblastic disease in Asian population of Northern England and North Wales.
Current understandings of the molecular genetics of gestational trophoblastic diseases.
Table-I: Demographic data of gestational trophoblastic disease (GTH) and control groups (meanSD, Standard Deviation).
Gestational trophoblastic disease in Sanliurfa, southeast Anatolia, Turkey.
P57kip2 immunohistochemical expression and ultra structural findings of gestational trophoblastic disease and related disorders.
1) UAVM can be difficult to diagnose, not only because they are rare, but because they may present similarly to or in conjunction with other pregnancy related pathologies, such as sub-involution of the placental bed, retained products of conception and gestational trophoblastic disease.
ACOG Practice Bulletin #53: diagnosis and treatment of gestational trophoblastic disease.
A total number of 95 women with sonography diagnosis of gestational trophoblastic disease, missed abortion, incomplete abortion and blighted ovum participated in the study.
Gestational transient thyrotoxicosis Choriocarcinoma Gestational trophoblastic disease * Partial hydatidiform mole * Complete hydatidiform mole
Such cases have 3 potential etiologies: (a) false-positive hCG due to interfering antibodies, (b) quiescent gestational trophoblastic disease, and (c) pituitary hCG.
Pelvic MR imaging findings in gestational trophoblastic disease, incomplete abortion, and ectopic pregnancy: are they specific?