The methylerythritol phosphate (MEP) pathway leads to the biosynthesis of geranylgeranyl diphosphate and the diterpenoid biosynthesis pathway (OKADA, 2007).
The geranylgeranyl diphosphate production in rice probable occur in the plastids by methylerythritol phosphate pathway, whereas sesquiterpenes and triterpenes are usually synthesized in the cytoplasm through the mevalonate pathway (VRANOVA et al.
A new geranylgeranyl diphosphate
synthase gene from Ginkgo biloba, which intermediates the biosynthesis of the key precursor for ginkgolides.
Likewise, Geranylgeranyl diphosphate
synthase (GGPPS) uses FPP as a substrate and adds another IPP to form Geranylgeranyl diphosphate
(GGPP) with 20 carbons.
They are made by the cyclization of geranylgeranyl diphosphate
(GGPP) to form the intermediate elisabethatriene, which is in turn converted to a variety of final products (Figure 6).
6,043,072) for a new gene coding for Taxus geranylgeranyl diphosphate
synthase, a pivotal enzyme in paclitaxel synthesis.