genome-wide association study


Also found in: Acronyms, Wikipedia.

genome-wide association study

A research study that compares all of the DNA of people affected by an illness with the DNA of matched healthy individuals. Its aim is to identify specific genetic variations that make some people more likely than others to become sick. These variations (mutations) are often minor, consisting of as little as a change in a single nucleotide in a DNA strand.
References in periodicals archive ?
A genome-wide association study of calf birth weight in Holstein cattle using single nucleotide polymorphisms and phenotypes predicted from auxiliary traits.
Single-step method: The ss-GBLUP was used to predict DGVs ([DGV.sub.ss]) and analyze genome-wide association study data (ssGWAS).
Novel association of ABO histo-blood group antigen with soluble ICAM-1: Results of a genome-wide association study of 6,578 women.
[3] Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium, "Genome-wide association study identifies five new schizophrenia loci," Nature Medicine, vol.
Nevertheless, this association pattern is in agreement with the results of a previous genome-wide association study in an Icelandic sample [31].
The genome-wide association study determined that every 1 mmol/L increase in fasting glucose associated with these genes increased the risk of coronary heart disease by 43%, Jordi Merino, PhD, said at the annual meeting of the European Association for the Study of Diabetes.
For the study, the team performed a genome-wide association study (GWAS) with DNA samples from 11,000 children.
ITPR2 as a susceptibility gene in sporadic amyotrophic lateral sclerosis: A genome-wide association study. Lancet Neurol 2007;6:869-77.
Other topics include image processing and artificial neural networks for the automated identification of plant species from leaf outlines, a genome-wide association study of biological shape based on elliptic Fourier analysis with a case study in rice gain shape variation, evolution and devolution in the spiral shell growth of gastropods, comparing robust generalized superimposition methods using three-dimensional facial images, and Fourier descriptors in a quantitative analysis of whole body outlines.
Genome-wide association study (GWAS) is a standard approach for studying the genetics of natural variation, typically focusing on association between single-nucleotide polymorphisms (SNPs) and traits.
A genome-wide association study reveals a quantitative trait locus of adiponectin on CDH13 that predicts cardiometabolic outcomes.

Full browser ?