like ichthyosis, aplasia congenita cutis, epidermolysis bullosa, incontinentia pigmenti, erythropoietic porphyria and mastocytosis are also present.
Babu, "Dyschromatosis universalis hereditaria: Infrequent genodermatoses
in India," Indian Journal of Human Genetics, vol.
Intrinsic factors Those with Xeroderma Pigmentosum (XP) are Genodermatoses
more susceptible to UVA radiation, which leads to skin and eye degeneration and the development of skin SCC, BCC, and MM Immunosuppression Chronic immunosuppression (e.g., long- term corticosteroid immunosuppression therapy or posttransplant therapy) increases skin cancer incidence.
A variety of vascular problems (2.4%) and genodermatoses
(1.2%) were seen.
Although BCC is the commonest human cancer, presentation with multiple or early-onset lesions should prompt consideration of an underlying Mendelian disorder (such as basal cell nevus syndrome or xeroderma pigmentosum) or other genodermatoses
characterized by defective DNA replication/repair, such as MTS.
Other risk factors are: exposure of the hands to ionizing radiation or carcinogenic chemicals, burns, genetic predisposition from specific genodermatoses
and immunosuppression .
No patient had features suggestive of genodermatoses
associated with predilection for cutaneous malignancies like xeroderma pigmentosa, albinism, and so forth.
3), leprosy, subcutaneous mycosis as mycetoma or sporotrichosis, as well as deforming genodermatoses
, are of particular concern--not only do they cause marked morbidity but they may lead to death.
This fourth volume is arranged in sections on anatomy, physiology, and embryology; benign growths; malignant growths; rashes; autoimmune blistering diseases; infectious diseases; hair and nail diseases; nutritional and metabolic diseases; and genodermatoses
(6.) Williams ML, Elias PM: Ichthyoses: genetic heterogeneity, genodermatoses
, and genetic counseling.
: Beckwith Wiedmann syndrome,--Hogg -Dube syndrome, familial atypical multiple mole melanoma syndrome, hereditary tylosis, incontinentia pigmenti and supernumerary nipples.
Although nevus anemicus is an isolated finding in normal healthy individuals, it may occur in association with genodermatoses
such as neurofibromatosis, and in conjunction with nevus flammeus and Mongolian spot in phakomatosis pigmentovascularis.