gene regulation

gene reg·u·la·tion

control of protein synthesis by means of activation or inhibition of that protein synthesis.
References in periodicals archive ?
The company said, "We continue to progress our strategy to develop our diversified portfolio of genomic medicine product candidates using our expertise in gene therapy, cell therapy, genome editing and gene regulation. Last month, we reported updated results for SB-525, our investigational gene therapy for hemophilia A.
Sangamo's zinc finger protein transcription factor (ZFP-TF) gene regulation technology is designed to either selectively repress (down-regulate) or activate (up-regulate) the expression of a specific gene or gene allele following a single administration.
Net proceeds from the offering will be used for working capital and other general corporate purposes, including support for its own and its partnered gene therapy, genome editing, cell therapy and gene regulation product candidates and research programmes, its manufacturing facilities and other business development activities.
"We discovered fasting influences the circadian clock and fasting-driven cellular responses, which together work to achieve fasting-specific temporal gene regulation," said lead author Paolo Sassone-Corsi, Donald Bren Professor of Biological Chemistry at UCI's School of Medicine.
Fulcrum Therapeutics is a biotechnology company developing new medicines to deliver a new future to patients and their families by transforming gene regulation in disease.
To ensure correct gene regulation additional kinds of proteins are required, such as enzymes that modify proteins that wrap around the DNA or even the DNA itself, thus fine tuning this complex process.
Coupling MS to ChIP will allow researchers to shed light on the proteomic landscape of the extracted chromatin enabling them to begin to understand how proteins interact with repressed and active regions of the genome and their role in global gene regulation. ChromaTrap, www.chromatrap.com, +44 1978 666222
In addition, MeiraGTx is developing novel gene regulation platforms that promise to transform the way gene therapy can be applied and create new paradigms for biologic therapeutics.
This is a recently-discovered type of gene regulation called RNA editing.
Nimer evaluate the ability of inhibitors or activators of epigenetic gene regulation to promote the differentiation, or inhibit the self-renewal, proliferation, and survival of RUNX1 mutant hematopoietic cells derived from cultures of human-induced pluripotent stem cells (iPSCs).
With this funding, ENCODE will expand the scope of its efforts to include characterization centers, which will study the biological role that candidate functional elements may play and develop methods to determine how they contribute to gene regulation in a variety of cell types and model systems.