promoter

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pro·mo·ter

(prō-mō'tĕr),
1. In chemistry, a substance that increases the activity of a catalyst.
2. In molecular biology, a DNA sequence at which RNA polymerase binds and initiates transcription.

promoter

(prə-mō′tər)
n.
1. One that promotes, especially an active supporter or advocate.
2. A financial and publicity organizer, as of a boxing match or an artistic performance.
3. Genetics The region of an operon that acts as the initial binding site for RNA polymerase.

pro·mo·ter

(prŏ-mō'tĕr)
1. chemistry A substance that increases the activity of a catalyst.
2. molecular biology A DNA sequence at which RNA polymerase binds and initiates transcription.

promoter

In genetics, a nucleotide sequence at the start of a gene to which RNA polymerase must bind before the process of transcription can start. The promoter is located UPSTREAM of the gene it regulates.

promoter

a cis- acting (see CIS -ACTIVE) NUCLEOTIDE sequence on a DNA molecule which promotes the initiation of TRANSCRIPTION by allowing the assembly of proteins, including RNA POLYMERASE (or its equivalent), in transcriptional complexes. see OPERON MODEL. The promoter generally lies UPSTREAM of the transcription start site.

Patient discussion about promoter

Q. I am interested in social service. So what can I do to promote a healthy pregnancy?

A. Hi friend, once you're pregnant, a regular checkup is the key. Your health professional might want to monitor your baby's growth and watch for problems that can only be detected by checking your blood pressure, urine, and blood regularly. Anything you do that harms your body harms your fetus. Take special care: To avoid: tobacco smoking, alcohol, drugs, chemicals, radiation (as from X-rays), and sources of infection. Keep your body temperature from getting too high [over 100.4° (38°)] by treating any fevers with acetaminophen (such as Tylenol) and avoiding exercise or activity that overheats you. Also avoid high-temperature hot tubs and saunas. Take extra-good care of yourself while you're pregnant. Everything healthy you do for your body benefits your growing fetus. Rest when you need it, eat well, and exercise regularly.

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References in periodicals archive ?
Significance of rs1271572 in the estrogenreceptor beta gene promoter and its correlation with breast cancer in a southwestern Chinese population.
* DNA methylation changes, including those reported here in the MMP11 gene promoter, may partially explain the different patterns of genetic risk factors that are sometimes observed between different population cohorts.
Because PBD3 is among the most responsive porcine HDP genes to butyrate and many other fatty acids and their analogs [20], the PBD3 gene promoter was selected for the development of a HTS luciferase assay.
Srinivasan, "Alterations in gene promoter methylation and transcript expression induced by cisplatin in comparison to 5-azacytidine in HeLa and SiHa cervical cancer cell lines," Molecular and Cellular Biochemistry, vol.
Supplementary Table 2: the genes with DMRs which were found to be located in the gene promoter by DiffMeth method analysis.
Milet et al., "Genetic polymorphisms of MMP1, MMP3 and MMP7 gene promoter and risk of colorectal adenoma," BMC Cancer, vol.
DNA methylation prevents transcription factors from getting close to the gene promoter region, leading to inhibiting gene expressions and rendering a gene into a silent state.
In addition, Hasan et al.5 found that AVPR1A gene promoter -6951 SNPs are closely associated with vasoconstrictor effect.
Higher levels of glucocorticoid receptor (GR) gene promoter methylation at pretreatment (indicating lower GR expression) were associated with a positive response to psychotherapy treatment.
In continuity with our previous observations [10], the aim of our study was to analyze methylation of GpG sites in the VDR gene promoter of a different and larger series of human adrenocortical tissues, comparing adrenocortical adenomas (ACAs) with ACCs samples.
After adding the drugs to the cell cultures, they checked the activity of the gene promoter for collagen type II, which makes up the majority of the cartilage protein in the joints (Col2a1), as well as the activity of a marker gene of chondrocytes (Aggrecan), and an important regulator of chondrogenesis (Sox9).