gemcitabine

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gemcitabine

 [jem-sit´ah-bēn]
an antineoplastic agent used in chemotherapy for pancreatic adenocarcinoma and non–small cell lung carcinoma; administered by intravenous infusion as the hydrochloride salt.

gemcitabine

/gem·cit·a·bine/ (jem-sit´ah-bēn) an antineoplastic agent used as the hydrochloride salt in the treatment of pancreatic adenocarcinoma and non.

gemcitabine

a miscellaneous antineoplastic.
indications It is used to treat adenocarcinoma of the pancreas (nonresectable Stages II and III or metastatic Stage IV) and non-small-cell lung cancer (Stages IIIA or B and IV). It is also used in combination with cisplatin to treat inoperable, advanced, or metastatic non-small-cell lung cancer.
contraindications Known hypersensitivity and pregnancy prohibit its use.
adverse effects Life-threatening effects are leukopenia, anemia, neutropenia, thrombocytopenia, and hemorrhage. Other adverse effects include diarrhea, nausea, vomiting, anorexia, constipation, stomatitis, irritation at the site of administration, rash, alopecia, dyspnea, fever, and infection.

gemcitabine

Gemzar Oncology An IV antimetabolic antineoplastic used with cisplatin for inoperable non-small cell lung CA, and as a single agent for inoperable pancreas CA Side effects ↓ WBCs and platelets; ↑ liver enzymes; 10% discontinued medication due to flu-like Sx, N&V, rash. See Cisplatin. Cf 5-FU.

gemcitabine

A CYTOTOXIC anticancer drug. A brand name is Gemzar.
References in periodicals archive ?
The chemotherapeutic regimens included Vinorelbine and Cisplatin/ carboplatin; Gemicitabine and Cisplatin/ carboplatin; Taxol and Cisplatin/ carboplatin; and Docetaxel and cisplatin.
Its products include 5-Fluorouacil, dotacexel, paclitaxel, cyclophosphamide, irinotecan, busulfan, lenalidomide, doxorubicin, thalidomide, imatinib myselate, tyrosine kinase inhib, gemicitabine, risperidone, vincristine and clozapine.