MMP9

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MMP9

A gene on chromosome 20q12-q13 that encodes matrix metalloproteinase 9, which degrades collagens IV and V, gelatins I and V, and fibronectin. It is thought to play a key role in local proteolysis of the extracellular matrix and in leukocyte migration, and may play a role in osteoclastic resorption of bone.

Molecular pathology
Defects in MMP9 increase susceptibility to intervertebral disc disease and lumbar disc herniation; MMP9 defects cause metaphyseal anadysplasia type 2.
References in periodicals archive ?
John Cleland of Somerfield, Sir Steve Redgrave, Barbara Gelb, chief executive of the Association of Children's Hospices, and David Strudley, chief executive of Acorns.
"Even back then some of us were wondering about the long-term emission and geopolitical ramifications of using so much gas and oil for transportation," Gelb claims.
The anchoring theory can explain the lightness compression effect found by Cataliotti and Gilchrist (1995; see also Gilchrist & Cataliotti, 1994) when presenting a luminance staircase in the context of experimental settings similar to the ones used in the famous Gelb demonstration (Gelb, 1929/1938; hereafter the "Gelb effect").
Gupta, * Martina Toby, ([dagger]) Gagori Bandopadhyay, ([double dagger]) Mary Cooke, * David Gelb, * and Jonathan S.
First-time Art & Design Licensing Gallery exhibitor Jacki Gelb of Gelb Illustration, says, "Exhibiting will give me the opportunity to bring the warm, playful quality of my designs to a broader audience.
GELB IS A STRAIGHT TALKER IN HIS MID-60S, with thinning white hair, an old-time New York accent, and an affection for Persian cats.
"In the foreign policy world, history is power," commented CFR president emeritus Leslie Gelb. "Who is right or wrong in the past either gives or withholds power today." The sobering truth revealed by this episode is that--whatever eventually happens to Kissinger's historical reputation--the CFR is still in charge of imposing the ruling elite's version of historical "truth."
Another is Saadia Gelb, now 90, a lifelong Labor Zionist and kibbutz movement activist who has lived at Kibbutz Kfar Blum since 1947.
While most childhood vaccines no longer contain mercury, aluminum might be harder to replace, says FDA spokesperson Lenore Gelb. So far, no one has identified a safe alternative that can perform the same way.
There are many pleasures to be had in reading Arthur Gelb's "City Room," his account of a lengthy career at the New York Times.
That's why Michael Gelb's How To Think Like Leonardo Da Vinci is so important: it provides a rebuttal that developing the mind isn't dependent upon genes alone, and it shows how to uncover hidden abilities to unlock latent creative potential for learning and creativity.
Abe Rosenthal and Arthur Gelb were running the Metropolitan desk back then, and they assigned McCandlish Phillips to the story.