Gaucher cell


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Gaucher cell

A large reticuloendothelial cell seen in Gaucher disease, which contains a small, eccentrically placed nucleus and kerasin.
References in periodicals archive ?
Subsequent death of the Gaucher cells creates an insoluble calcium soap, which leads to an area of increased medullary density on radiographs.
Bone marrow examination revealed the presence of lipid-engorged macrophages, typical Gaucher cells appeared with “fibrillary crumpled silk” in the cytoplasm and eccentrically placed nucleus.
3) However, the needle-shaped crystalloid nature of the inclusions in CSH can be easily distinguished from the fibrillarity seen in Gaucher cells.
1] Gaucher disease has long been confused with CSH, although Gaucher cells have paler, so-called wrinkled-paper cytoplasm.