Gardos channel

Gardos channel

A cell membrane pore that regulates intracellular volume with a pump that forces potassium ions out of the cell. The pump is activated by calcium ions.
References in periodicals archive ?
Considered to be a group of very rare diseases, the number of reported cases of HX in the past three years is increased after the identification of the causative genes, such as PIEZO1 [9-11] and, more recently, KCNN4 codifying for Gardos channel [20-23].
Picard et al., "A mutation in the Gardos channel is associated with hereditary xerocytosis," Blood, vol.
Gallagher, "Mutations in the Gardos channel (KCNN4) are associated with hereditary xerocytosis," Blood, vol.
The drug, known as ICA-17043, is part of new class of drugs known as Gardos channel inhibitors.
The drug, known as ICA-17043, is part of new class known as Gardos channel inhibitors.