In about 50% of asymptomatic women, culture results are positive for flora such as Gardnerella vaginalis
. (5) While Amsel's criteria are often used as a reference and generally suffice for the evaluation of symptomatic women, the best candidate for a gold standard test is probably Gram stain assessment using Nugent's criteria (described in this section).
The common organisms causing Leucorrhoea are Candida albicans, Trichomonas vaginalis and Gardnerella vaginalis
, Atopobium vaginae, and Prevotella and Lactobacillus species made up 81% of the isolates.
Bacterial vaginosis represents disruption of the vaginal flora, with overgrowth of anaerobic and facultative organisms such as Gardnerella vaginalis
, Mycoplasma hominis, Atopobium vaginae, and other species.
Gram negatives will overgrow, and Gardnerella vaginalis
genitalium (13), herpes simplex viruses (HSV-1 and -2), Trichomonas vaginalis, Ureaplasma urealyticum and parvum, Gardnerella vaginalis
, and adenoviruses (12).
When those levels become unbalanced, the normal flora may be overgrown by anaerobic microorganisms (non-oxygen dependent organisms), mycoplasmas and Gardnerella vaginalis
. The result is a low-grade infection that often produces an abnormal vaginal discharge.
is not really attacked by metronidazole," he said.
infection, or bacterial vaginosis, has been suggested in a number of studies as a cofactor for the development of cervical intraepithelial neoplasia and as being associated with an increased relative risk of developing cervical intraepithelial neoplasia.
Bacterial Vaginosis [BV] is the most common variety of vaginal infection in which the normal predominant vaginal flora Lactobacillus is replaced with Gardnerella vaginalis
, anaerobic bacteria and Mycoplasma hominis.