gamma-hydroxybutyric acid

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γ-hydroxybutyric acid

Central nervous system depressant causing relaxation, loss of muscle tone and reduced inhibitions. Effects are enhanced when mixed with alcohol. Previously sold in health food stores as a performance-enhancing drug until banned by the FDA in 1990. Sometimes vernacularly termed date rape drug.
References in periodicals archive ?
Stimulatory effects of gamma-hydroxybutyric acid on growth hormone and prolactin release in humans.
Pharmacokinetics of gamma-hydroxybutyric acid in alcohol-dependent patients after single and repeated oral doses, British Journal of Clinical Pharmacology (1992) 34:231-235.
Gamma-hydroxybutyric acid for treatment of opiate withdrawal syndrome, Neuropsychopharmacology (1993) 9:77-81.
Gamma-hydroxybutyric acid in the treatment of alcohol dependence: A double-blind study, Alcoholism, Clinical and Experimental Research (1992) 16:673-676.
Gamma-hydroxybutyric acid in the treatment of alcohol and heroin dependence, Alcohol (2000) 20:257-262.
Abuse and therapeutic potential of gamma-hydroxybutyric acid, Alcohol (2000) 20:263-269.
A tale of novel intoxication: A review of the effects of gamma-hydroxybutyric acid with recommendations for management, Annals of Emergency Medicine (1998) 31:729-736.
A sudden awakening from a near coma after combined intake of gamma-hydroxybutyric acid (GHB) and ethanol, Journal of Toxicology Clinical Toxicology (1997) 35:591-594.
Dose-dependent absorption and elimination of gamma-hydroxybutyric acid in healthy volunteers, European Journal of Clinical Pharmacology (1993) 45:353-356.
Formation and regional distribution of gamma-hydroxybutyric acid in mammalian brain, Biochemical Pharmacology (1970) 19:3013-3019.
Gamma-hydroxybutyric acid: patterns of use, effects and withdrawal.
From the street to the brain: Neurobiology of the recreational drug gamma-hydroxybutyric acid. Trends in Pharmacological Science 25 (1): 29-34.
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