gamma-butyrolactone


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γ-butyrolactone

Industrial solvent and purported health additive. Precursor in the synthesis of γ-hydroxybutyric acid.
Farlex Partner Medical Dictionary © Farlex 2012

gamma-butyrolactone

(găm′ə-byo͞o′tə-rə-lăk′tōn′)
n. Abbr. GBL
A chemical that has many industrial uses, especially as a solvent. It is a chemical precursor to gamma-hydroxybutyrate and is ingested illegally for its euphoriant and sedative effects.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

gam·ma-bu·ty·ro·lac·tone

(GBL) (gam'ă-byū'tir-ō-lak'tōn)
An industrial and household solvent that is readily metabolized after oral ingestion to gamma-hydroxybutyrate (GHB). Like GHB, it is marketed illicitly as a euphoriant, appetite suppressant, antidepressant, and sleep aid. It is more potent than GHB and has both a more rapid onset and a longer duration of action, but its pharmacologic and toxic properties are essentially the same: nausea, bradycardia, and central nervous system depression ranging from drowsiness and confusion to seizures, coma, and death. Dependency and severe withdrawal symptoms have been reported.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
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References in periodicals archive ?
The illicit home synthesis from gamma-butyrolactone and sodium hydroxide, sold together in kits, has been the source of numerous cases of GHB overdose (Henretig et al.
Mum Maryon Stewart wants an inquiry into why gamma-butyrolactone (GBL) has not been banned in Britain.
Det Insp Andy Hawkins said: "We believe the controlled substance Gamma-Butyrolactone, or GBL, may have been used as a drug at the gathering." A spokesman for drugs charity FRANK said: "GBL is a dangerous drug with sedative and anaesthetic effects that can produce feelings of euphoria and can cause drowsiness.
Police said a postmortem has yet to be held but added: "We believe that controlled substance gamma-butyrolactone, or GBL, may have been used as a drug at the gathering at the address."
GBL - gamma-butyrolactone - will be classified as a Class C drug.
Hester Stewart, 21, died after mixing gamma-butyrolactone (GBL) with alcohol.
Gold dust (cocaine) Grass(weed) Green (ketamine) GBL (gamma-butyrolactone) GBL is a dangerous drug with sedative effects, also known as 'coma in a bottle'.
Ganja (weed) Gear (heroin) Glass (crystal meth) Gold dust (cocaine) Grass(weed) Green (ketamine) GBL (gamma-butyrolactone) GBL is a dangerous drug with sedative effects, also known as 'coma in a bottle'.
There were at least four ambulance cars lined up and loading people in the back." GBL, or Gamma-Butyrolactone, is used by some partygoers to achieve a legal high.

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