G protein

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G protein

A cellular protein activated by the binding of an intercellular signal to its receptor on the cell membrane; the G-protein then activates the enzyme adenyl cyclase within the cell, triggering the formation of cyclic AMP and a stereotyped response.
See also: protein
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
Lastres-Becker, "Transcription factors NRF2 and NF-kB are coordinated effectors of the Rho family, GTP-binding protein RAC1 during Inflammation," Journal of Biological Chemistry, vol.
Fujisawa et al., "The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase," The EMBO Journal, vol.
small Ran-related GTP-binding protein; calmodulin 4 which is a regulatory protein controlled by calcium; nucleoside diphosphate kinase that regulates metabolic pools of nucleoside diphosphates; histones that control chromosome organization; heat-shock proteins that regulate a plant cell's response to stress.
Garcia-Ranea et al., "The small GTP-binding protein, Rhes, regulates signal transduction from G protein-coupled receptors," Oncogene, vol.
Crystal structure of the GTP-binding protein Obg from Thermus thermophilus HB8.
Kato et al., "Involvement of Rho p21 small GTP-binding protein and its regulator in the HGF-induced cell motility," Oncogene, vol.
(1991) Identification of two novel GTP-binding protein alpha-subunits that lack apparent ADP-ribosylation sites for pertussis toxin.
An interesting phenomenon was that some proteins that are associated with cell growth, proliferation, differentiation, apoptosis, and death Isomatotropin, developmentally regulated GTP-binding protein 2, insulin-like growth factor binding, ATP-binding protein associated with cell differentiation, and interleukin-1[beta]-converting enzyme (ICE)-like apoptotic protease 5 [Fas-associating protein with Death Domain (MORT1)associated Caenorhabditis elegans cell death gene (CED-3) homolog] were correlated with age.
Bordetella bronchiseptica dermonecrotizing toxin induces reorganization of actin stress fibers through deamidation of Gln-63 of the GTP-binding protein Rho.
Rho-associated protein kinase (ROCK) is a well-characterized effector of Rho GTPase, a small GTP-binding protein. The Rho/ROCK signaling pathways contribute to a wide range of fundamental cellular events, such as cell adhesion, motility, proliferation, differentiation, and apoptosis.
Singh, "Cloning and characterization of GTP-binding proteins of Mycobacterium tuberculosis H37Rv," Enzyme and Microbial Technology, vol.
Moreover, the nuclear factor, erythroid 2 like 2- (NFE2L2-) related pathway (NFE2L2 is also known as Nrf2), GTP-binding proteins, and epigenetic modifications have also attracted increasing attention in recent years [7-9].