ALG11

(redirected from GT8)

ALG11

A gene on chromosome 13q14.2 that encodes GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase, an enzyme localised to the cytosolic side of the endoplasmic reticulum that catalyses the transfer of the 4th and 5th mannose residue from GDP-mannose (GDP-Man) to Man3GlcNAc2-PP-dolichol and Man4GlcNAc2-PP-dolichol, resulting in the production of Man5GlcNAc2-PP-dolichol.

Molecular pathology
ALG11 is mutated in congenital disorder of glycosylation type Ip (CDGIp).
References in periodicals archive ?
The season ticket holders, who had long held tickets in the GT8 stand of the Lower Gwladys Street, were all relocated to other seats - but many were unhappy with the move.
And it's in that famous stand that the club are introducing their next change - withEvertonrevealing a singing section will be introduced to GT8 next term.
The line-up includes specials such as the Vantage GT8 as well as the firm's GT endurance cars like the one Scottish driver Jonny Adam used to win the 2018 British GT Championship.
A recent computational analysis of these sequences suggested that they may be conformationally similar to the glycosyltransferase GT8 family.
The sales figures include the sell-out demand for its DB11 model and special vehicles including the Vanquish Zagato and Aston Martin Vantage GT8, said a statement.
Aston Martin Holdings (UK) Ltd, the producer of luxury handcrafted sports cars, today announced that it sold 5,117 sports cars last year amid sell-out demand for its DB11 model and special vehicles including the Vanquish Zagato and Aston Martin Vantage GT8.
"Cars such as the Vantage GT8 and Vantage GT12 confirmed that our customers love raw, racebred models, but we also knew there was an opportunity to create cars that offer a sharper performance focus but stop short of those truly hard-core, special series models.
Aston Martin president and chief executive, Dr Andy Palmer said: "Cars such as the Vantage GT8 and Vantage GT12 confirmed that our customers love raw, race-bred models, but we also knew there was an opportunity to create cars that offer a sharper performance focus but stop short of those truly hard-core, special series models.
We have also become world leaders in ultra-low volume projects with cars such as the One-77, Lagonda Taraf and Aston Martin Vulcan, while the Vantage GT12 and Vantage GT8 show how far we can take our series production models.
The legendary British sports car manufacturer also gave its Vantage GT8 - the lightest and most powerful V8-powered Vantage ever built - its first UK public runs at Goodwood, driven in Saturday's timed run category by Aston Martin Racing works driver, Darren Turner.
Just 150 examples of the Vantage GT8 will be produced, each priced from PS165,000.
Auto Business News-April 19, 2016--Aston Martin launches GT8