GSK3B(redirected from GSK3beta isoform)
GSK3BA gene on chromosome 3q13.3 that encodes a serine-threonine kinase of the glycogen synthase kinase subfamily, which is involved in glycogen metabolism, proliferation, motility, survival, neuronal development and body pattern formation.
GSK-3 plays a role in diabetes, cancer and neurologic disease—GSK3B polymorphisms are implicated in Parkinson disease; GSK3B overexpression may play a role in Alzheimer’s disease.
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