GSK-3 alpha | definition of GSK-3 alpha by Medical dictionary
GSK3A (redirected from GSK-3 alpha)
GSK3A A gene on chromosome 19q13.2 that encodes a multifunctional protein serine kinase, which participates in the control of various regulatory proteins, including glycogen synthase and transcription factors (e.g., JUN, and plays a role in the WNT and PI3K signalling pathways.
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References in periodicals archive
Further exploration of the apparent interrelationship of insulin resistance to brain amyloidosis reveals a functional decrease in insulin receptor- (IR-) mediated signal transduction in the brain; Akt/PKB inhibits glycogen synthase kinase (GSK-3 alpha
) activity .