GPR65 | definition of GPR65 by Medical dictionary
GPR65 A gene on chromosome 14q31-q32.1 that encodes a G protein-coupled receptor for psychosine and related glycosphingolipids; GPR65 may have a role in activation-induced cell death or in T-cell differentiation.
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References in periodicals archive
Interestingly, we were able to determine that GPR65 is associated with cardiovascular diseases .
Bruggemeier, "Diagnostics and therapeutics for diseases associated with the gpr65 receptor," Google Patents, 2003.
Recent studies suggest that OGR1-family GPCRs, including OGR1 (GPR68), GPR4, and T cell-death associated gene 8 (TDAG8 or GPR65
), also sense extracellular protons and, thereby, stimulates a variety of cellular activities through several types of G proteins [18-21] (Figure 1).