PRLHR

(redirected from GPR10)

PRLHR

A gene on chromosome 10q26.13 that encodes a G coupled-protein receptor for prolactin-releasing hormone, which is highly expressed in the anterior pituitary.
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Mice lacking its receptor, the G-protein-coupled 10 receptor (GPR10), become obese (83).
GPR10 deficiency in mice results in altered energy expenditure and obesity.
ICV NMB inhibits food intake in rodents Gastrin-releasing Anorexigenic GRP is produced in the PVN and peptide (GRP) increases after infusion of the MC4R agonist MTII, suggesting its role is downstream of the MC4R Prolactin-releasing Anorexigenic, PrRP acts through the GPR10. peptide (PrRP) increase in ICV PrRP decreases food intake energy and increases energy expenditure expenditure.