Some experts have demonstrated that genetic polymorphisms of platelet membrane glycoproteins (GPI1
, GPIba, GPIIIa, and GPIV) may influence the efficacy of aspirin or platelet responsiveness, and genetic polymorphisms of the thromboxane A2 receptor (TBXA2R), platelet-activating factor acetylhydrolase, and coagulation factor XIII were associated with platelet aggregation.
The Orlean group identified the yeast GPI1 gene, which is also involved in the first step.
(1996) Gpi1, a Saccharomyces cerevisiae protein that participates in the first step in glycosylphosphatidylinositol anchor synthesis.
Westfall et al., "The first step of glycosylphosphatidylinositol biosynthesis is mediated by a complex of PIG-A, PIG-H, PIG-C and GPI1," EMBO Journal, vol.
Orlean, "Gpi1, a Saccharomyces cerevisiae protein that participates in the first step in glycosylphosphatidylinositol anchor synthesis," The Journal of Biological Chemistry, vol.
My average fuel burn is 32 GPI1
and 36 GPH at lower altitude flights.