GPR172A

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GPR172A

A gene on chromosome 8q24.3 that encodes a riboflavin transporter, which also acts as a receptor for porcine endogenous retrovirus subgroup A (PERV-A).

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G protein coupled receptors (such as GPCR41 and GPCR43) expressed on the surface of neutrophils identify PAMP and promote neutrophil aggregation, ultimately contributing to the development of steroid resistance in neutrophilic asthma phenotypes [85-87].

Pathological Roles of Neutrophil-Mediated Inflammation in Asthma and Its Potential for Therapy as a Target

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