Busciglio et al., "Genetic variation in GPBAR1
predisposes to quantitative changes in colonic transit and bile acid excretion," American Journal of PhysiologyGastrointestinal and Liver Physiology, vol.
Huang, "The G-protein-coupled bile acid receptor, Gpbar1
(TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor kappa light-chain enhancer of activated B cells (NF-kB) in mice," Hepatology, vol.
Gene symbol Gene name GO biological process TPP ITIH1 Inter-alpha-trypsin Hyaluronan metabolic inhibitor heavy chain 1 process PCK1 Phosphoenolpyruvate Glucose metabolic process carboxykinase 1 FABP4 Fatty acid binding Cholesterol homeostasis 4 protein GPBAR1
G-protein-coupled bile Cell surface bile acid acid receptor 1 receptor signaling pathway PPP1R1A Protein phosphatase 1 Glycogen metabolic regulatory inhibitor process subunit 1A SLC04C1 Solute carrier organic Cell differentiation anion transporter family, member 4C1 FNDC5 Fibronectin type III Response to muscle domain-containing protein activity 5 ADIPOQ Adiponectin.
Fiorucci, "Reversal of endothelial dysfunction by gpbar1
agonism in portal hypertension involves a AKT/FOXOA1 dependent regulation of H2S generation and endothelin-1," PLoS ONE, vol.