GP150 | definition of GP150 by Medical dictionary
ITGB4 (redirected from GP150)
ITGB4 A gene on chromosome 17q25 that encodes an integrin beta chain protein (integrins are noncovalently associated transmembrane glycoprotein receptors, composed of alpha and beta chains). The beta chain encoded by ITGB4 usually associates with alpha 6, serving as a laminin receptor. It plays a key structural role in the hemidesmosomes, regulates keratinocyte polarity and motility and is a central player in the biology of invasive cancer.
ITGB4 mutations are associated with epidermolysis bullosa with pyloric atresia.
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References in periodicals archive
Facey, "CD13 (GP150
; aminopeptidase-N): predominant functional activity in blood is localized to plasma and is not cell-surface associated," Experimental Hematology, vol.
Prior to inflation, the GP150
is so small you'll forget you're wearing it and when inflated you'll be truly glad that you are.
(20) The second plasmid expressed an HIV-1 subtype C truncated envelope protein (Env, gp150
I had a Lambretta GP150
scooter, which enabled me to get there ahead of everyone else.
Human myeloid plasma membrane glycoprotein CD13 (gp150
) is identical to aminopeptidase N.