GNB1

GNB1

A gene on chromosome 1p36.33 that encodes a beta subunit of a heterotrimeric guanine nucleotide-binding protein (G protein), which regulates signal transduction between receptors and effectors.
References in periodicals archive ?
(31,32) The most commonly involved genes include DNMT3A, TET2, and ASXL1; however, other frequently mutated genes include TP53, JAK2, SF3B1, GNB1, PPM1D, GNAS, and BCORL1.
Additionally, transcriptional analysis of the effect of deletion of GNB1 and GNG1 as well as the phosducin-like protein PHLP1 showed that glycosyl hydrolases are the major targets of light-dependent signaling by heterotrimeric G-proteins [109].