GM2gangliosidosis

G_M2gan·gli·o·si·do·sis

(gang'glē-ō-si-dō'sis)

One of the hereditary metabolic disorders; several forms exist, including Tay-Sachs disease, Sandhoff disease, AV variant and adult onset; characterized by accumulation of a specific metabolite, G_M2 ganglioside, due to deficiency of hexosaminidase A or B, or G_M2 activator factor.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012