GRIA1

(redirected from GLUR1)

GRIA1

A gene on chromosome 5q33 that encodes a member of the excitatory neurotransmitter glutamate receptor family, which are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) and function as ligand-activated cation channels.

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References in periodicals archive ?

Cocaine-induced behavioral sensitization in adolescent rats endures until adulthood: lack of association with GluR1 and NR1 glutamate receptor subunits and tyrosine hydroxylase.

Behavioral cross-sensitization between testosterone and fenproporex in adolescent and adult rats

Notably, Ras-GTP (a kinase in the ERK pathway) has been shown to induce trafficking of GluR1 to synapses [151], and GSK3[beta] promotes membrane localization of NMDA receptors [152].

Circadian Regulation of Hippocampal-Dependent Memory: Circuits, Synapses, and Molecular Mechanisms

Takahashi et al., "Beta-amyloid accumulation in APP mutant neurons reduces PSD-95 and GluR1 in synapses," Neurobiology of Disease, vol.

Contribution of Neurons and Glial Cells to Complement-Mediated Synapse Removal during Development, Aging and in Alzheimer's Disease

1 protein mediates reconsolidation of morphine CPP by increased GluR1 cell surface expression: activation of ERK-coupled CREB is required.

Animal models of drug addiction/Modelos animales de adiccion a las drogas

The role of nitric oxide and GluR1 in presynaptic and postsynaptic components of neocortical potentiation.

Chronic Allium sativum administration alters spontaneous alternation and cyto-architecture of medial prefrontal cortex of adult Wistar rats

Reversal of cocaine-induced behavioral sensitization and associated phosphorylation of the NR2B and GluR1 subunits of the NMDA and AMPA receptors.

Developing treatments for stimulant abuse: a brief overview

Sakai et al., "Nobiletin, a citrus flavonoid with neurotrophic action, augments protein kinase A-mediated phosphorylation of the AMPA receptor subunit, GluR1, and the postsynaptic receptor response to glutamate in murine hippocampus," European Journal of Pharmacology, vol.

A Potential Alternative against Neurodegenerative Diseases: Phytodrugs

Possible role of platelet GluR1 receptors in comorbid depression and cardiovascular disease.

Changes of Serotonin (5-HT), 5-HT2A Receptor, and 5-HT Transporter in the Sprague-Dawley Rats of Depression, Myocardial Infarction and Myocardial Infarction Co-exist with Depression

Topiramate reduces AMPA-induced Ca(2+) transients and inhibits GluR1 subunit phosphorylation in astrocytes from primary cultures.

Advances in medications and tailoring treatment for alcohol use disorder

In the same way, glutamate subunits GluR1 and NR1 are reduced, causing a profound deregulation in synapse-related proteins and behavior, marked deficits in social interaction behavior and an increased anxiety in the open field (Hermes, Li, Duman & Duman, 2011).

Social interaction and conditional self-discrimination under a paradigm of avoidance and positive reinforcement in Wistar rats/Interaccion social y auto-discriminacion condicional bajo un paradigma de reforzamiento positivo y evitacion en ratas Wistar

High abundance of GluR1 mRNA and reduced Q/R editing of GluR2 mRNA in individual NADPH-diaphorase neurons.

Potentiation of morphine analgesia with co-administration of nimodipine in rat, tail-flick test study: implication in the treatment of chronic pain

Abbomax has developed a panel of six anti-GluR antibodies: GluR1, GluR2/3, GluR4, GluR6/7, mGluR1, mGluR5.

Panel of Six New Anti-Glutamate Receptor Antibodies from AbboMax and Their Function in the Central Nervous System and Other Organs