GLUD2

GLUD2

An intronless gene on chromosome Xq24-q25 that encodes glutamate dehydrogenase 2, a mitochondrial enzyme which forms a homohexamer to recycle glutamate during neurotransmission, catalysing the reversible oxidative deamination of glutamate to alpha-ketoglutarate. It is expressed in the retina and testes.
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21) Likewise, the genes ASPM and MCPH1 are implicated in the size of the brain, as well as PDYN, GLUD2, COX8, and CMAH which may change brain regulation, cerebral metabolism, and so forth.
Our genetic prehistory: Did genes make us human?
The PIPSL gene (also an interesting hybrid gene) was inserted into the DNA of a great ape ancestor, and the GLUD2 gene in an ape ancestor.
Human evolution: how random process fulfils divine purpose
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