GLUD1

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GLUD1

A gene on chromosome 10q23.3 that encodes glutamate dehydrogenase 1, a mitochondrial matrix enzyme which catalyses the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. It plays a key role in regulating amino acid-induced insulin secretion. GLUD1 is allosterically activated by ADP and inhibited by GTP and ATP; it may be involved in learning and memory by increasing the turnover of the neurotransmitter glutamate.

Molecular pathology
Missense mutations of GLUD1 cause hyperinsulinemic hypoglycaemia type 6.
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References in periodicals archive ?
According to Greg Frisby, Global Industry Manager of SpecMetrix Systems at Sensory, "Glud & Marstrand has been a recognized world leader in global packaging solutions based upon a commitment to innovation and the continuous improvement of their processes and products.
Although numerous ecophysiological studies have examined boreal and Arctic algal species, few studies to date have studied these algal species in situ (Chapman and Craigie, 1977; Dunton and Schell, 1986; Rysgaard and Glud, 2007).
You can contact Torben Glud our senior sales manager on +971 55 9423 886.
(1986), Grubbstrom and Thorstenson (1986), Glud Johansen and Thorstenson (1996), Klein Haneveld and Teunter (1998), Teunter and van der Laan (2002), Grubbstrom and Kingsman (2004), Bogataj et al.
In 2010, researchers led by Ronnie Glud of the University of Southern Denmark sent a remotely operated deep-sea lander to the western Pacific Ocean to explore the Mariana Trench's Challenger Deep--at 11 kilometers down, the deepest seafloor on Earth.
So, even though deep sea trenches like the Mariana Trench only amount to about two percent of the World Ocean area, they have a relatively larger impact on marine carbon balance - and thus on the global carbon cycle, said Professor Ronnie Glud from Nordic Center for Earth Evolution at the University of Southern Denmark.
"Rather, we find a world dominated by microbes that are adapted to function effectively at conditions highly inhospitable to most higher organisms," said team leader Ronnie Glud from the University of Southern Denmark's Nordic Centre for Earth Evolution.
"If we retrieve samples from the seabed to investigate them in the laboratory many of the micro-organisms that have adapted to life at these extreme conditions will die due to the changes in temperature and pressure," Ronnie Glud from the Nordic Centre for Earth Evolution at the University of Southern Denmark said.
The November 2002 issue of Holography News[R] reported on its front page that Danish packaging manufacturer Glud & Marstrand (G&M) had released promotional demonstrations of the integrated hologram 'tin can' that they have developed over several years working with Jan Stensborg of Stensborg Inc and the Centre for Advanced Technology.
This second model maps the aforementioned tensions specifically in relation to Web 2.0; but also serves as a way of guiding designs for Web 2.0 learning (Buus et al., 2010; Glud et al., 2010, Ryberg et al., 2009; Ryberg et al, 2010b).
Teimlaf fod hanes diweddar a hanes llafar yn mynd law yn llaw 'r archaeoleg yn yr achos yma a dyma ddilyn Eflyn i'w myfyrfa fach glud yng nghefn y tye a dechrau clywed yr hanes, ei hatgofion fel plentyn a hefyd hanes yr holl waith ymchwil a chenhadu mae Eflyn wedi bod yn ei wneud ar ran Llyn Cerrig Bach dros y blynyddoedd.