SLC1A3

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SLC1A3

A gene on chromosome 5p13 that encodes solute carrier family 1 member 3, a high-affinity glutamate transporter that plays a key role in transporting glutamate across plasma membranes. In the brain, these transporters clear the excitatory neurotransmitter glutamate from the extracellular space at synapses in the CNS and maintain extracellular glutamate concentrations below neurotoxic levels.
 
Molecular biology
SLC1A3 mutations are associated with episodic ataxia, Type 6.
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The Gamma-ray Large Area Space Telescope (GLAST), NASA's next high-energy astrophysics satellite, achieved a major milestone last year when engineers completed the main detector array.
Guided by the finer resolution afforded by radio and X-ray instruments, GLAST will detect radiation from the jets' base, allowing astronomers to deduce the jets' overall shape, the types of particles they accelerate, and how they accelerate those particles.
In our previous studies, different hyperbaric pressure levels (15 mmHg additional pressure/30 mmHg additional pressure/45 mmHg additional pressure/60 mmHg additional pressure) were used to test Muller cell survival and GLAST protein expression.
We have previously reported that deletion of the ASK1 gene prevents RGC death in various mouse models of glaucoma, including retinal ischemia, optic nerve injury (ONI), and GLAST KO mice (GLAST/ASK1 double KO mice) [15,35,36].
Doi et al., "Increase in glutamateaspartate transporter (GLAST) mRNA during kanamycin-induced cochlear insult in rats," Hearing Research, vol.
Muller cells have high affinity L glutamate\ L aspartate transporter (GLAST) expression and plays an important role in transport of extracellular glutamate through GLAST transporter from the synaptic spaces of the retina.
(81) Mice deficient in the glutamate/ aspartate transporter (GLAST), a major glutamate transporter in the retina, display optic nerve degeneration and are used as model mice for normaltension glaucoma.
But since the phenomenon has never been observed, the upcoming launch of the GLAST (Gammaray Large Area Space Telescope) satellite again looms large in significance.
Thomas Purcell III is a professor of accounting and professor of law at Creighton University in Omaha, NE, Kenneth Horwitz is of counsel at Glast, Phillips Si Murray RC, in Dallas, TX.
Copperwave, Joan Tower; Il Ritorno, Robert Dennis; The Three Tenses, Huang Ruo; Reflecting Light, Adam Schoenberg; GLAST Prelude, Nolan Gasser; Cornopean Airs, Paul Moravec.
Fest fun: Damon and Harry, top, and Edith and Rudy, above, chill out at Glasto Glast off: Rolf raps, Kasabian rock while Sophie, and Jamie enjoy fest
GLAST OFF: Fan strip to bikinis and sunhats yesterday