GJA5


Also found in: Acronyms.

GJA5

A gene on chromosome 1q21.1 that encodes an alpha chain of the gap junction protein family or connexins. 

Molecular pathology
GJA5 mutations have been associated with atrial fibrillation.
References in periodicals archive ?
For example, Gja5 (Cx40) and Gjd3 (Cx31.9) were downregulated in GK and unaltered in STZ SAN; Trpc6 (TRPC6) was downregulated in GK and upregulated in STZ SAN; Ryr2 (RYR2) was upregulated in GK and unaltered in STZ SAN; Hcn1 (HCN1) and Hcn4 (HCN4) were downregulated in GK and unaltered in STZ SAN; Cacna1d ([Ca.sub.v]1.3), Cacna1h (Cav3.2), and Cacng4 ([Cav.sub.[gamma]]4) were downregulated in GK SAN; however, in the STZ study, Cacna1d was unaltered, Cacna1h was upregulated, and Cacng4 was downregulated; Kcna5 ([K.sub.v]1.5) and Kcnk1 (TWIK1) were downregulated in GK SAN and unaltered in STZ SAN; Nppb (BNP) was upregulated in GK and in STZ SAN.