GJA4

GJA4

A gene on chromosome 1p35.1 that encodes an alpha chain of the gap junction protein family or connexins.
 
Molecular pathology
GJA4 mutations are linked to atherosclerosis and an increased risk of myocardial infarction.
References in periodicals archive ?
ACOT2 CFD GCSH LACTB RASSF2 ACY1 CITED2 GJA4 LRP8 RSAD2 ADAMTS9 CRYAB GSTP1 LRRC58 RUNX2 ALCAM CTGF HACD4 NFKB1 SLC26A7 ANKRD9 CXCL1 HSD17B1 NR3C2 SMIM22 ARHGAP22 DGAT2 IGFBP5 NRIP3 SPARC BHLHE40 EGR1 IGFBP7 NUP107 STS BRAF EIF4E IRGQ OPRK1 TAZ CAMK1G ENPP1 JUN OSTALPHA TEKT4 CAMKK2 F10 KCNJ15 PBLD TG CD47 FAM13A KCNJ16 POMT1 TMEM140 CDA FGFR2 KCNK1 PRR5L TRIB1 CDH16 FOXE1 KRT14 RAB17 WBP2 CDH16 GALK2 KRT7 RASL10A WNT4
In particular, the gene GJA4 (gap junction protein, [alpha]4, 37 kDa) was described as associated with cardiovascular and coronary heart disease outcomes.
[5] Human genes: ESR1, estrogen receptor 1 (formerly ESR); ESR2, estrogen receptor 2 (ER R); KCNHS, potassium voltage-gated channel, subfamily H (eag-related), member 5; GJA4, gap junction protein, [alpha]4, 37 kDa (formerly CX37).