GJA1


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Related to GJA1: Cx43

GJA1

A gene on chromosome 6q21-q23.2 that encodes an alpha chain of the gap junction protein family, or connexins.

Molecular pathology
GJA1 mutations are associated with oculodentodigital dysplasia and cardiac malformations.
References in periodicals archive ?
We performed a series of molecular investigations and reviewed the literature with the aim of validating the clinical utility of testing for GJB2, GJB6 and GJA1 in the African context.
Connexin43 (GJA1) is required in the population of dividing cells during fin regeneration.
When the genes for the ion channels GJA1 and KCNJ2 were silenced, these proteins were shown to be important in mediating the miR-1-induced arrhythmogenic effect (61).