GJA1 | definition of GJA1 by Medical dictionary
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GJA1 A gene on chromosome 6q21-q23.2 that encodes an alpha chain of the gap junction protein family, or connexins.
GJA1 mutations are associated with oculodentodigital dysplasia and cardiac malformations.
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References in periodicals archive
We performed a series of molecular investigations and reviewed the literature with the aim of validating the clinical utility of testing for GJB2, GJB6 and GJA1
in the African context.
) is required in the population of dividing cells during fin regeneration.
When the genes for the ion channels GJA1
and KCNJ2 were silenced, these proteins were shown to be important in mediating the miR-1-induced arrhythmogenic effect (61).