GHB


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GHB

GHB

abbr.
gamma-hydroxybutyrate

anabolic steroid

A drug or hormone-like substance chemically or pharmacologically related to 17-α-alkylated testosterone that promotes muscle growth, which are commonly abused by athletes. Lipid changes by ASs are more marked with oral stanazol (manufactured for horses) than with IV testosterone; it decreases HDL-C (especially HDL2) and increases hepatic TG lipase (HDL) catabolism.
 
Indications
Children, adolescents with delayed puberty, decreased growth, small penis, hypogonadism, testosterone deficiency, osteoporosis management, aplastic anaemia, endometriosis, angioedema, sports performance enhancement (no longer legal), relief and recovery from common injuries, rehabilitation, weight control, anti-insomnia, and regulation of sexuality, aggression and cognition.

Route
Oral, parenteral.
 
Metabolic effects
Increased protein synthesis and amino acid consumption, androgenesis, catabolism and gluticocototitosis.
 
Adverse effects (men)
Breast enlargement (gynecomastia), testicular atrophy, sterility, sperm abnormalities, impotence, prostatic hypertrophy, myocardial hypertrophy and fibrosis, myocardial infarction and fatal arrhythmias, peliosis hepatis, cholestasis, hepatic adenomas, testicular atrophy, peripheral oedema, intracerebral thrombosis.

Adverse effects (women)
Clitoral hypertrophy, beard growth, baldness, deepened voice, decreased breast size.

Adverse effects (men and women)
Aggression and antisocial behavior, increased risk of cardiovascular disease, peliosis hepatis, haemorrhage, jaundice, acne, accelerated bone maturation resulting in short stature, liver tumours (hepatic adenomas and CA) which may regress with abstinence; AS abusers are at an increased risk for HIV transmission, given the common practice of sharing of needles when injecting ASs.

Lab
ASs are detectable to 1 parts per billion 4 days after last use if the hormone is water-soluble, or 14 days after use in lipid-soluble compounds.

FDA status
ASs are schedule-III drugs per the Controlled Substances Act.

GHB

1. Gamma-hydroxybutyrate, γ-hydroxy-butyrate. See GABA.
2. Glycosylated hemoglobin, see there.

GHb

Glycosylated hemoglobin, see there.

GHB

Abbreviation for gamma (γ)-hydroxybutyrate.

GHB

Abbreviation for γ-hydroxybutyrate.
References in periodicals archive ?
"The first time as an organisation we came across it was when we were working with men who were at chemsex parties and GHB, crystal meth and mephedrone were being used," he says.
Firstly, GHB use, even in those who did not undergo a coma, was associated with alterations in the identification of negative emotions.
Numbers in this group were small; 7 of 100 GHB and 15 of 100 Medicaid patients entered prenatal care with high-risk pregnancies.
The aim would be to see if brain imaging of people on a very low-carb diet has similar effects on brain activity seen when (https://www.nature.com/npp/journal/vaop/naam/abs/npp2017110a.html) people take GHB.
However, I suggest keeping an extra hat, pair of mittens or gloves, and other similar items in your GHB during those times of year when they'd likely be needed.
In the 1970s, scientists began consider using GHB to treat narcolepsy.
" But after spending the night in the open, we are being told that there will be no distribution of forms." GHB chairman Jayanti Barot said rumours spread by some people were to be blamed for the incident.
Driscoll admitted everything apart from the cocaine was his and stated that he was a GHB addict.
Mochrie admitted a charge of supplying GHB on that evening and also admitted that he later lied to police.
"Hawkins and an accomplice downloaded the recipe for GHB from the internet.
GBL turns into GHB, also known as liquid ecstasy, in the body after it's taken.