GLUD1

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GLUD1

A gene on chromosome 10q23.3 that encodes glutamate dehydrogenase 1, a mitochondrial matrix enzyme which catalyses the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. It plays a key role in regulating amino acid-induced insulin secretion. GLUD1 is allosterically activated by ADP and inhibited by GTP and ATP; it may be involved in learning and memory by increasing the turnover of the neurotransmitter glutamate.

Molecular pathology
Missense mutations of GLUD1 cause hyperinsulinemic hypoglycaemia type 6.
References in periodicals archive ?
The proof is via a reduction from the GDH problem which is believed to be hard.
Table 1 shows summary of comparison with other DH-based key management protocols: CKD, GDH, BD, STR, and TGDH.
In the present study, results are in agreement with previous observations regarding Cr(VI) induced GDH inhibition in leaves, stem, and root of sorghum [18].
GDH currently has 5 megawats of electricity confirmed from DEWA to power the first of the development's 1000 sq m halls.
As announced in July, Generali had agreed to acquire a 3% stake in GDH from private investors for EUR105.00 apiece and also unveiled plans to begin a squeeze-out procedure for the remaining 4%.
"GDH is one of the finest efforts at peering into the distant future.
[31.] Skuce, PJ, Stewart, EM, Smith, WD and Knox, DP, "Cloning and characterization of glutamate dehydrogenase (GDH) from the gut of Haemonchus contortus", Parasitology 1999; 118: 297-304.
Between February 18, 2010, and March 19, 2010, consecutive, nonformed stool samples submitted Monday through Friday to West Virginia University Hospital (WVUH) Clinical Laboratories, Morgantown, West Virginia, for C difficile toxin testing by routine EIA (Wampole C difficile Tox A/B; Inverness Medical Diagnostics, Princeton, New Jersey) were also tested in parallel with the GeneXpert C difficile real-time PCR assay (Cepheid Diagnostics, Sunnyvale, California) and a rapid lateral flow immunochromatographic GDH assay (C difficile Quik Chek Complete; Techlab, Blacksburg, VA).
agnau saktir brahmaghnas trir avacchatasya I laksyariz vet syCzj janye Sastratthrteun khatvidrigakaplilapCznir vd dvadata sarhvatsaroin brahtnaciiri bhaiksclya gramariz pravilet karmacaksanah I (GDh 22.2-4) Emaciated, a Brahmin-killer should cast himself into a fire three times; or he should become a target for armed men in battle; or for twelve years, he should carry in hand a khatviiriga and skull, remain celibate, and enter a village to beg alms while proclaiming his deed.
difficile toxins A (TcdA) and B (TcdB), as well as the CD-specific antigen glutamate dehydrogenase (GDH).
With the Gross Domestic Happiness (GDH) Index, no one domain is more important than any other.