GATA2

(redirected from GATA-binding protein 2)

GATA2

A gene on chromosome 3q21.3 that encodes a member of the GATA family of zinc finger transcription factors, which plays a key role in regulating transcription of genes involved in the development and proliferation of haematopoietic and endocrine cell lineages, and in regulating endothelin-1 gene expression.
References in periodicals archive ?
Abbreviations: CT, cryptotanshinone; RA, retinoic acid; Tro, troglitazone; C/EBP, CCAAT/enhancer-binding protein; PPAR[gamma], peroxisome proliferation-activity receptor [gamma]: GAPDH, glycerol-3-phosphate dehydrogenase; IBMX, isobutyl-1-methylxanthine; MTT, 3-(4 5-dimethylthiazol-2-yl)-2 5-diphenyltetrazolium bromide; GLUT4, glucose transporter type 4; TNF-[alpha], tumor necrosis factor a: CHOPIO, C/EBP-homologous protein 10; GATA2, GATA-binding protein 2; STAT3, signal transducer and activator of transcription 3; aP2, adipocyte protein 2; MCE, mitotic clonal expansion.