GATA6

(redirected from GATA-binding factor 6)

GATA6

A gene on chromosome 18q11.1-q11.2 that encodes a member of the GATA family of zinc finger transcription factors, which is thought to play a key role in regulating proliferation and terminal differentiation.
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Targets prediction revealed that miR-92a targeted both GATA family of zinc finger transcription factor GATA-binding factor 6 (GATA6) and insulin receptor substrate proteins 2 (IRS-2).
[sup][3] Ovarian theca cells, which express key enzymes of androgen production, such as 17-hydroxylase/C17-20 lyase cytochrome P50 (CYP17), and their transcription factors, for example, GATA family of zinc finger transcription factor GATA-binding factor 6 (GATA6), are the major place of androgen producing in ovary.