GATA1

(redirected from GATA binding protein 1)

GATA1

A gene on chromosome Xp11.23 that encodes a protein of the GATA family of transcription factors, which plays a key role in erythroid development by regulating the switch of foetal to adult haemoglobin.

Molecular pathology
GATA1 mutation is associated with X-linked dyserythropoietic anaemia and thrombocytopaenia.
References in periodicals archive ?
The plasmids containing Flag-tagged human GATA binding protein 1 (GATA1) and GATA binding protein 2 (GATA2) in pCMV6-Entry vector were obtained from OriGene Technologies (Rockville, MD, USA).