LGALS4

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LGALS4

A gene on chromosome 19q13.2 that encodes a galectin family-type carbohydrate-binding protein, which modulates cell-cell and cell-matrix interactions. LGALS is only expressed in the (large and small) intestine, and is under-expressed in colorectal cancer.
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References in periodicals archive ?
Flies crossed to GAL4 drivers (GAL4 drivers crossed to UAS-RNAi lines) and controls (GAL4 drivers or UAS-RNAi crossed to w1118) were raised at 25oC until the adults emerged (F1 generation); once collected adults were raised at 29oC for the appropriate times.
EFFECTS OF HEAT SHOCK AND GAL4 ON DROSOPHILA OOGENESIS.
Gal4 BD-PDZD7, Gal4 AD-[beta]-catenin, Gal4 AD-AMOT, or Gal4 AD-CADM1 alone did not activate the reporter gene HIS3.
Full-length PB1-F2 complementary DNA (cDNA) was cloned into pGBKT7 downstream of the Gal4 gene in fusion as bait, and a pGAD-based human lymphoid cDNA library (Clontech) was used for screening AH109 yeast cells according to the manufacturer's protocol.
When transcriptional PIC was formed at 25[degrees]C, both wild-type and med6-ts2 Pol II holoenzymes showed 23- and 21-fold activation of GAL4 enhancer-containing template (GAL4:G-) by Gal4-VP16 over basal transcription from GCN4:G-template, respectively (Figure 4, lanes 1 and 2).
Ptashne, "Specific DNA binding of GAL4, a positive regulatory protein of yeast," Cell, vol.
The cell culture assays were performed after transfection of (i) pBIND-PPAR[beta]/[delta], expressing Gal4-DBD and PPAR[beta]/[delta]-LBD fusion protein, and (ii) pGRE-LUC, which contains a Gal4 response element followed by firefly luciferase reporter gene.
cDNAs corresponding to FULL (225 amino acids), NTR (N-terminal region of 1-118 amino acids), and CTR (C-terminal region of 119-225 amino acids) were inserted into the EcoRI and PstI sites of pGBKT7 (Clontech, USA) fusing with the GAL4 DNA-binding domain.
The Gal4 (yeast transcription activator protein) fused to the PPAR[gamma] ligand-binding domain (LBD) and a firefly luciferase construct under the control of UAS (upstream activating sequence) were used.
The IRMA network data is a subnetwork embedded in Saccharomyces cerevisiae consisting of 5 genes: CBF1, GAL4, SWI5, GAL80, and ASH1.
An efficient binary system for gene expression in the silkworm, Bombyx mori, using GAL4 variants.