PIGU

(redirected from GAB1)

PIGU

A gene on chromosome 20q11.22 that encodes a component of the glycosylphosphatidylinositol (GPI) transamidase complex possibly involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.
References in periodicals archive ?
Many group 2 tumors show both GAB1 and YAP1 expression by immu nohistochemistry.
GAB1 is expressed in the cytoplasm of nearly all SHH medulloblastomas but not in other groups, and can be detected immunohistochemically, making it a valuable SHH-group marker.