ISG15

(redirected from G1P2)

ISG15

A gene on chromosome 1p36.33 that encodes a ubiquitin-like protein which binds to target proteins in response to IFN-alpha or IFN-beta stimulation. ISG15 has chemotactic activity on neutrophils and activates them, triggering their release of eosinophil chemotactic factors. It may: play a role as a trans-acting binding factor, directing ligated target proteins to bind to intermediate filaments; have autocrine, paracrine and endocrine effects, including cell-to-cell signalling, possibly by inducing IFN-gamma secretion by macrophages; respond to IFN-tau secreted by the foetus; and bind and regulate proteins involved in the release of prostaglandin F2-alpha, preventing lysis of the corpus luteum and maintaining the pregnancy.
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An ex 35 weeker, dichorionic-diamniotic twin A, was born to a 26-year-old G1P2 via caesarean section for pregnancy induced hypertension.
(...) Entao, a diversao dele, o lazer dele e passar a tarde inteira jogando ou video game ou jogo no computador (G1P2).
Dentre as sete narracoes, uma de cada participante, cinco fizeram referencia a alguma viagem que realizaram (G1P1; G1P2; G1P4; G2P6; e G2P7); uma contou um dia em que participou de varias festas na companhia do namorado (G1P3); e uma narrou um dia em que ficou em casa sozinha assistindo a filmes em sequencia (G2P5).
(G1P2) Atraves das falas e possivel perceber que os pais de fato exercem influencias, mas ha uma tendencia para que essa situacao mude com o passar do tempo, assim como verificaram Sarriera et al.
(...) (G1P2) Assim, as falas das jovens demonstraram que, para elas, existe uma relacao direta entre o lazer e o dinheiro, sendo este um criterio fundamental para a definicao das atividades proporcionadores de diversao, realizada por cada individuo.
(...) Esse medo que a gente tem hoje de pegar um taxi de madrugada ou, sei la, de ir de onibus de madrugada de um lugar para o outro, porque voce pode ser assaltada (G1P2).
(G1P2) Hoje eu ja conquistei uma certa autonomia ...
CASE REPORT: A 25 years old female G1P2, weighing 55 kg was admitted for delivery.
In this study on glioma cells, the activation of numerous interferon-induced proteins (such as IFIT1, IFIT2, IFI27, IFITM1, IFITM2, and G1P2) lends support to this mechanism of pathogenicity.
The other confirmed transcriptionally up-regulated genes may be associated with cervical disease: G1P2 (interferon-stimulated protein; 15-kDa) may be overproduced as a result of infection (24), and KRT14 and KRT16 (keratin 14 and 16) are produced at high concentrations in the keratinizing squamous epithelium of the cervix.
Patient identifier (b) Gene symbol (a) Pt 1 (c) Pt 2 Pt 3 Pt 4 Pt 5 CCNB1 +++ +++ + ++ +++ KRT14 +++ +++ + ++ +++ KARS +++ = + +++ + KRT16 ++ +++ = = +++ OAZ1 + +++ ++ ++ +++ SPINT2 + +++ + +++ +++ ZWINT ++ +++ +++ * +++ G1P2 +++ +++ ++ - - - +++ AURKB + 0 + = +++ CDCA8 ++ 0 + = + HPV16E7 +++ +++ 0 + 0 Patient identifier (b) Patients with up-regulated Gene symbol (a) Pt 6 Pt 7 Pt 8 gene, (d) n CCNB1 +++ + ++ 8 KRT14 = +++ + 7 KARS +++ +++ -- 6 KRT16 +++ +++ +++ 6 OAZ1 ++ = = 6 SPINT2 +++ = -- 6 ZWINT = +++ + 6 G1P2 - - 0 +++ 5 AURKB ++ 0 0 4 CDCA8 + 0 0 4 HPV16E7 +++ 0 0 4 (a) Genes listed were chosen for analysis by TagMan.