G1
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G1
Symbol for gap1 period.
G1
a phase in the cell cycle during which the cell's future can be influenced by various positive and negative signals, such as growth factors. The signals determine whether the cell will advance beyond a certain checkpoint. Once beyond the checkpoint, the cell is committed to entering a phase during which it replicates its DNA in preparation for mitosis.
AIF1
A gene on chromosome 6p21.3 that encodes allograft inflammatory factor 1, an actin-binding, cytokine- and interferon-induced protein that regulates proliferation of vascular smooth muscle cells, resulting in an anti-inflammatory response to vessel wall trauma.AIF1 activities
• Enhances lymphocyte migration and actin-bundling activity of LCP1.
• Plays a role in RAC signalling, phagocytosis and in vascular inflammation.
• Promotes proliferation of vascular smooth muscle cells and of T cells.
• May play a role in macrophage activation and function.