gamma-glutamyltransferase

(redirected from G-glutamyltransferase)

γ-glu·tam·yl·trans·fer·ase

(glū-tam'il-trans'fĕr-ās),
An enzyme that catalyzes the transfer of a γ-glutamyl group from a γ-glutamyl peptide (usually glutathione) to another peptide, certain amino acids, or water; a deficiency of this enzyme will result in glutathionuria.
References in periodicals archive ?
The patient's laboratory data revealed the infection and hepatic dysfunction during the current admission: white blood cells, 11.1 x 109/L (4-10x109/L); neutrophils, 86.5% (51-75%); alanine aminotransferase, 159.4 U/L (5-40U/L); aspartate aminotransferase, 50.2 U/L (8-40U/L); alkaline phosphatase, 338.9 U/L (47-185U/L); g-glutamyltransferase, 612.9 U/L (11-50U/L); direct bilirubin, 11.4umol/L (1.7-6.8umol/L).
However, there were elevated levels in globulin, alkaline phosphatase, alanine aminotransferase, aspartate aminotransferase, g-glutamyltransferase, potassium, urea, and creatinine.
Hepatic alkaline phosphatase and g-glutamyltransferase activities were significantly reduced in animals fed with SP + E diet and glucose-6-phosphatase activity was significantly enhanced.
(d) IDL, intermediate-density lipoprotein; ALT, alanine aminotransferase; ALP, alkaline phosphatase; GGT, g-glutamyltransferase. (e) P <0.001, with respect to control subjects.