nitrofurantoin(redirected from Furantoin)
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a broad-spectrum antibacterial agent used in treatment of urinary tract infections.
A urinary antibacterial agent with a wide range of activity against both gram-positive and gram-negative organisms; also available as nitrofurantoin sodium for injection.
nitrofurantoin/ni·tro·fu·ran·to·in/ (-fu-ran´to-in) an antibacterial effective against many gram-negative and gram-positive organisms; used in urinary tract infections.
A derivative of nitrofuran, C8H6N4O5, used to treat bacterial infections of the urinary tract.
a urinary antibacterial.
indications It is prescribed in the treatment of urinary tract infections caused by some gram-negative bacteria and a few gram-positive bacteria. Some of the more common bacteria that cause urinary tract infections are resistant to it.
contraindications Kidney dysfunction or known hypersensitivity to this drug prohibits its use. It is not given to children under 1 month of age or to pregnant or lactating women. It should be used with caution in people with glucose-6-phosphate dehydrogenase deficiency, vitamin B deficiency, anemia, diabetes mellitus, or electrolyte disturbances.
adverse effects Among the most serious adverse effects is hypersensitivity pneumonitis, which can lead to fibrosis, neurotoxicity, and hemolytic anemia in patients with glucose-6-phosphate dehydrogenase deficiency. GI disturbances and fever are common.
A nitrofuran compound (O-[5-nitrofurfurylideneamino]hydantoin) with antimicrobial activity against a wide spectrum of gram-positive and gram-negative bacteria.
nitrofurantoinA drug that damages bacterial DNA and is used to treat urinary tract infections. The drug is on the WHO official list. Brand names are Furadantin, Macrobid and Macrodantin.
Urinary antibacterial agent with a wide range of activity against both gram-positive and gram-negative organisms.
a nitrofuran derivative antibacterial agent used in the treatment of urinary tract infections.