258 presumptive cases of Microbial keratitis were sent to the microbiology laboratory for investigations, of these 258 presumptive cases 105(40.69%) cases were confirmed microbiologically either by microscopy and/ or culture as bacterial or fungal keratitis
13 (9%), Escherichia coli 9(6%) and Enterobacter spp 6(4%) while Aspergillus fumigates represented 26(30%) as the most common cause of fungal keratitis
, Aspergillus flavus 19(22%), Aspergillus niger 16(18%), Pencillium spp 11(13%), Fusarium oxysporium.
Laboratory in the Diagnosis of Bacterial and Fungal Keratitis
. In Common Eye Infections, 2013; In Tech.
is caused mainly by two types of pathogens: yeast and mold.
This prospective study was carried out at the department of ophthalmology of Chandka Medical College and Hospital, Larkana, Pakistan, from March 2005 to March 2016, and comprised patients suspected to have fungal keratitis
. Approval was obtained from the ethics review committee of Shaheed Mohtarma Benazir Bhutto (SMBB) Medical University, Larkana.
flavus ATCC 204304 which may be possible causes of fungal keratitis
(22,23) were used to evaluate antifungal activity of developed formulations.
[sup] Fungal keratitis
is the combined result of pathogen and host factors, such as long-term use of broad-spectrum antibiotics, dysbacteriosis in the conjunctival sac, or application of corticosteroids, leading to local hypoimmunity or corneal trauma cases.
is an uncommon disease in avian patients.
The absence of fungal keratitis
in our series might be attributed to the fact that majority of the patients came from an urban background and did not have a history of trauma with vegetative material as is classically seen in cases with fungal keratitis
Corneal injury predisposing to fungal keratitis
(91.9%; 1046 of 1138) was significantly higher, compared to other predisposing risk factors (8.1%; 92 of 1046) (P<0.0001) (OR: 73.5; 95% CI: 61.3-98.5).
"Clinicians should be vigilant in diagnosing and treating fungal keratitis
, and users of MoistureLoc should discontinue the use of this product," the CDC investigators said (JAMA 2006;296:953-63).
Neighborhood-matched controls were adults reporting soft contact lens use during March 2006 with no history of fungal keratitis
. Information regarding contact lens types, solutions used, and contact lens hygiene practices was obtained via telephone interviews conducted by trained personnel who used standardized questionnaires.