active site

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ac·tive site

that portion of an enzyme molecule at which the actual reaction proceeds; considered to consist of one or more residues or atoms in a spatial arrangement that permits interaction with the substrate to effect its reaction.
Farlex Partner Medical Dictionary © Farlex 2012

active site

The part of an enzyme at which catalysis of the substrate occurs.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

Active Site

The site in an enzyme where a substrate binds and an enzymatic reaction—e.g., ligation, oxidoreduction, etc.—occurs. The structure of the amino acid residues within the active site enhances substrate binding, substrate activation, and formation of a transition state.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

ac·tive site

(ak'tiv sīt)
That portion of an enzyme molecule at which the actual reaction proceeds; one or more residues or atoms in a spatial arrangement that permits interaction with the substrate.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

active site

1. The region of an ENZYME to which the substance being affected binds so as to undergo a catalyzed reaction.
2. The localized part of a protein to which a substrate binds.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
Active siteclick for a larger image
Fig. 11 Active site . Lock-and-key mechanism of enzyme activity.

active site

an area of ENZYME surface which has a shape complementary to a particular SUBSTRATE, enabling the enzyme and substrate to become temporarily bonded to form an enzyme-substrate complex. Such a lock-and-key mechanism explains the great specificity of enzymes for substrates and also why changes in enzyme three-dimensional shape (by pH, temperature) cause alterations to enzyme activity.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

Patient discussion about active site

Q. Are there any nice activities for adults with autism? I've been helping a very nice man of 45 of years old and I'm looking for some new things I can do with him in our time together. any ideas?

A. Autistic people react wonderfully with animals. for instance- i saw a group of severe Autistic teenagers going to swim with dolphins. the effect was amazing! taking him to the zoo, or even to the park to feed ducks, pet dogs, whatever.. could have a great effect on him.
hope i helped!
tell me how it went.

Q. what is a passive smoking? and is it dangerous as an active?

A. Passive smoking is the exposure to cigarettes smoke emitted from cigarettes smoke by other person. It's dangerous and may increase the risk to several diseases similar to active smoking (one's exposure to smoke emitted from the cigarettes he or she is smoking) although the risk is of lower magnitude. Example for passive smoking is children of smokers etc.

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Q. i swim a lot ! what are the advantages of swimming over other sport activities? on what part of the body does it work the most ?

A. its a good workout but your not really going to burn as much calories as a regular work out.

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References in periodicals archive ?
Prediction of Functional group in the OGG1 protein D1 and D2 structures: Based on the eukaryotic motif resources and putative functional sites, protein functional sites can be predicted based on expression patterns.
* Complete needed maintenance to current UCP Seguin residential homes and centers across the region, ensuring the provision of safe, accessible and functional sites.
To evaluate the amount of acidic and basic functional sites present on the surface of the RDB and MDB, Boehm Titration was carried out.
Talking to reporter, an official of WFP Pakistan said the Programme was supporting nutritional support to the IDP families to Khyber Agency at 17 functional sites and to South Waziristan at 32 functional sites through government, FATA Health Directorate and Secretariat and non-governmental organizations.
He credited Macy's, Bed Bath & Beyond and WaLmart for having highly functional sites and Macy's and Walm art for having the most aggressive strategies for online.
The frequency of MSM occurrence near functional sites seems to exceed the average for the amino acid sequences of natural proteins, and it has been suggested that MSM may play a role in the formation of functional sites of proteins, as well as in protein oligomerization [8, 9].
In this study, evolutionary trace (ET) method which relies on both amino acid sequence and structural information to analyze functional sites of proteins is used because of the advantage of having molecular and structural information in a single analysis 11].
Such broadly neutralizing antibodies typically work by blocking crucial functional sites on a virus that are conserved among different strains despite high mutation elsewhere.
On the other hand, signal sensors try to predict the presence of functional sites. Many algorithms are used for gene prediction including: dynamic programming, hidden Markov models (HMMs), artificial neural networks (ANNs) and linear discriminate analysis.
The creators of business organising software 1DayLater wanted to set up a project which allowed businesses to network while providing functional sites for charities which might have an outdated or non-existent web presence.
For example, the G[alpha]-subunit can be myristoylated at the N-terminus end for proper plasma membrane localization of G[alpha], and functional sites can regulate the interactions of G[alpha] with G[beta][gamma], effectors, and G-protein regulators (Lukov et al., 2004).
"Control of Location and Concentration of Functional Sites for Thermosetting Latexes" -- M.D.

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