Fumagillin | definition of fumagillin by Medical dictionary
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A molecule produced by fungi that prevents new blood vessel formation (“angiogenesis”), and may be useful in treating cancers.
an antibiotic produced by Aspergillus fumigatus. Used in bees to control the parasite, Nosema.
References in periodicals archive
Thrombocytopenia is the main adverse event of fumagillin
therapy, occurring in up to 33% of patients (j) and raising concerns about fumagillin
use in patients with hematologic disorders.
Potent anti-angiogenic action of AGM-1470: comparison to the fumagillin
and its analogs have been used topically to treat corneal infections and orally for gastrointestinal microsporidiosis (27), but because of possible side effects, they have not been used to treat microsporidial myositis (27).