Mr Saldanha, who works at Singleton Hospital in Swansea, explained: "Fuchs' endothelial dystrophy
is quite common in the local Caucasian population.
Objective assessment of the corneal endothelium in Fuchs' endothelial dystrophy
. Invest Ophthalmol Vis Sci 2014; 55: 1184-90.
In this study, we had prospectively evaluated 1-year clinical outcomes of the first 50 consecutive DMEKs performed at one centre versus 50 consecutive DSEK surgeries performed during the same time period on patients with endothelial decompensation due to pseudophakic, aphakic bullous keratopathy and Fuchs' endothelial dystrophy
Intraocular pressure and corneal biomechanics in Fuchs' endothelial dystrophy
and after posterior lamellar keratoplasty.
Ehlers, "Descemet's stripping automated endothelial keratoplasty and penetrating keratoplasty for Fuchs' endothelial dystrophy
," Acta Ophthalmologic, vol.
Oxidative stress is known as a vital pathogenesis underlying aging and many human ocular diseases, such as corneal diseases (injuries, keratoconus, Fuchs' endothelial dystrophy
(FECD), etc.), dry eyes, cataracts, glaucoma, age-related macular degeneration, and other oxidative-related diseases in the eyes .
Subjects with previous intraocular surgery, contact lens use, corneal trauma or other corneal pathologies which might affect the corneal endothelium, including Fuchs' endothelial dystrophy
, were excluded from the study.
Fuchs' endothelial dystrophy
is one of the main indications for endothelial keratoplasty.
We herein report our experience with CXL using two different methods in 2 patients with Fuchs' endothelial dystrophy
Frequent indications to endothelial corneal grafting include Fuchs' endothelial dystrophy
, bullous keratopathy following phacoemulsification, and endothelial disfunction after corneal transplant.
Failure is similar in nature to Fuchs' endothelial dystrophy
in that it is a decompensation of the endothelial layer resulting in oedema with associated haze and possible bullae (see Figure 3).
Conditions such as Fuchs' endothelial dystrophy
(FED) or pseudophakic bullous keratopathy (PBK) may lead to irreversible corneal edema and, consequently, loss of vision.